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Heyde's syndrome

Medical condition

Heyde's syndrome is a syndrome of gastrointestinal bleeding from angiodysplasia in the presence of aortic stenosis. It is named after Edward C. Heyde, MD, who first noted the association in 1958. It is caused by cleavage of Von Willebrand factor (vWF) due to high shear stress forces from aortic valvular stenosis.

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